Catabolite repression control of pyocyanin biosynthesis at an intersection of primary and secondary metabolism in Pseudomonas aeruginosa.

نویسندگان

  • Jiaofang Huang
  • Elisabeth Sonnleitner
  • Bin Ren
  • Yuquan Xu
  • Dieter Haas
چکیده

In Pseudomonas aeruginosa, the catabolite repression control (Crc) protein repressed the formation of the blue pigment pyocyanin in response to a preferred carbon source (succinate) by interacting with phzM mRNA, which encodes a key enzyme in pyocyanin biosynthesis. Crc bound to an extended imperfect recognition sequence that was interrupted by the AUG translation initiation codon.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 78 14  شماره 

صفحات  -

تاریخ انتشار 2012